TAN-1323 C and D, New Concanamycin-group Antibiotics; Detection of the Angiostatic Activity with a Wide Range of Macrolide Antibiotics.
نویسندگان
چکیده
منابع مشابه
TAN-1323 C and D, new concanamycin-group antibiotics; detection of the angiostatic activity with a wide range of macrolide antibiotics.
We detected potent angiostatic activity in a MeOH extract from the mycelia of microbial strain S-45628 in the chick chorioallantoic membrane (CAM) assay. The producer was taxonomically characterized as Streptomyces purpurascens. Active principles designated TAN-1323 A-D were isolated and determined to be 18-membered macrolide antibiotics; components C and D are new members of this group, while ...
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Anti-inflammatory activity of macrolide antibiotics.
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متن کاملTAN-1496 A, C and E, diketopiperazine antibiotics with inhibitory activity against mammalian DNA topoisomerase I.
Fungal metabolites with an epi-oligothiadiketopiperazine structure, TAN-1496 A, C and E, were isolated from the culture broth of Microsphaeropsis sp. FL-16144. Their molecular formulas were determined to be C22H28N2O9S2, C22H28N2O9S3 and C22H28N2O9S4, respectively. Structures were determined by comparing the NMR data with those of known diketopiperazine antibiotics, sirodesmins. These metabolit...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1995
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.48.12